REVIEW PAPER
Tobacco use increases susceptibility to bacterial infection
Donald R Demuth 1, 2,  
David A Scott 1, 3, 2  
 
 
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1
Department of Microbiology and Immunology, University of Louisville, Louisville, USA
2
Oral Health and Systemic Disease Research Group, University of Louisville, Louisville, USA
3
Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA
Publish date: 2008-12-18
 
Tobacco Induced Diseases 2008;4(December):12
KEYWORDS:
ABSTRACT:
Active smokers and those exposed to secondhand smoke are at increased risk of bacterial infection. Tobacco smoke exposure increases susceptibility to respiratory tract infections, including tuberculosis, pneumonia and Legionnaires disease; bacterial vaginosis and sexually transmitted diseases, such as chlamydia and gonorrhoea; Helicobacter pylori infection; periodontitis; meningitis; otitis media; and post-surgical and nosocomial infections. Tobacco smoke compromises the anti-bacterial function of leukocytes, including neutrophils, monocytes, T cells and B cells, providing a mechanistic explanation for increased infection risk. Further epidemiological, clinical and mechanistic research into this important area is warranted.
 
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Jordi Almirall, José Blanquer, Salvador Bello
Archivos de Bronconeumología
70. Tobacco Upregulates P. gingivalis Fimbrial Proteins Which Induce TLR2 Hyposensitivity
Juhi Bagaitkar, Donald R. Demuth, Carlo Amorin Daep, Diane E. Renaud, Deanne L. Pierce, David A. Scott, Adam J. Ratner
PLoS ONE
71. Risk factors for thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype
M. M. T. J. Broekman, M. J. H. Coenen, G. J. Wanten, C. J. van Marrewijk, O. H. Klungel, A. L. M. Verbeek, P. M. Hooymans, H.-J. Guchelaar, H. Scheffer, L. J. J. Derijks, D. R. Wong, D. J. de Jong
Alimentary Pharmacology & Therapeutics
72. Pathobiologic Mechanisms of Chronic Obstructive Pulmonary Disease
Anthony Tam, Don D. Sin
Medical Clinics of North America
73. Application of Nanotechnology in Water Research
Farheen Khan, Rizwan Wahab
74. The prevention of infection-associated cancers
S. De Flora, P. Bonanni
Carcinogenesis
75. Health care-associated infections in patients with head and neck cancer treated with chemotherapy and/or radiotherapy
Aurora Mirabile, Chiara Vismara, Fulvio Crippa, Paolo Bossi, Laura Locati, Cristiana Bergamini, Roberta Granata, Carlo Resteghini, Eutilia Conte, Daniele Morelli, Paolo Scarpellini, Lisa Licitra
Head & Neck
76. Legionella pneumonia in the Niagara Region, Ontario, Canada: a case series
Stephanie Cargnelli, Jeff Powis, Jennifer L. Y. Tsang
Journal of Medical Case Reports
77. Exposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam
Reiko Miyahara, Kensuke Takahashi, Nguyen Thi Hien Anh, Vu Dinh Thiem, Motoi Suzuki, Hiroshi Yoshino, Le Huu Tho, Hiroyuki Moriuchi, Sharon E. Cox, Lay Myint Yoshida, Dang Duc Anh, Koya Ariyoshi, Michio Yasunami
Scientific Reports
78. Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance
Luis G. Vargas Buonfiglio, Jennifer A. Borcherding, Mark Frommelt, Gavin J. Parker, Bryce Duchman, Oriana G. Vanegas Calderón, Ruth Fernandez-Ruiz, Julio E. Noriega, Elizabeth A. Stone, Alicia K. Gerke, Joseph Zabner, Alejandro P. Comellas
Respiratory Research
79. Recruitment of α7 nicotinic acetylcholine receptor to caveolin-1-enriched lipid rafts is required for nicotine-enhancedEscherichia coliK1 entry into brain endothelial cells
Feng Chi, Lin Wang, Xueye Zheng, Ambrose Jong, Sheng-He Huang
Future Microbiology
80. Tobacco Smoking as a Risk Factor for Increased Antibiotic Prescription
Michael B. Steinberg, Ayse Akincigil, Eun Jung Kim, Rory Shallis, Cristine D. Delnevo
American Journal of Preventive Medicine
81. Bone marrow mesenchymal stem cells ameliorate lung injury through anti-inflammatory and antibacterial effect in COPD mice
Hong-mei Liu, Yi-tong Liu, Jing Zhang, Li-jun Ma
Journal of Huazhong University of Science and Technology [Medical Sciences]
82. Steroid-Decorated Antibiotic Microparticles for Inhaled Anti-Infective Therapy
Sie Huey Lee, Jeanette Teo, Desmond Heng, Yanli Zhao, N.G. Wai Kiong, Hak-Kim Chan, Reginald B.H. Tan
Journal of Pharmaceutical Sciences
83. Outcomes, complications, utilization trends, and risk factors for primary and revision total elbow replacement
Andrew J. Lovy, Aakash Keswani, James Dowdell, Steven Koehler, Jaehon Kim, Michael R. Hausman
Journal of Shoulder and Elbow Surgery
84. Variations inNeisseria meningitidiscarriage by socioeconomic status: a cross-sectional study
P.R. Cleary, N. Calvert, S. Gee, C. Graham, S. Gray, E. Kaczmarski, J. Morphet, L. Murphy, N. Verlander, T. Wood, R. Borrow
Journal of Public Health
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