Smoking cessation attempts: is it useful to treat hard core smokers?
C. Quantin 1,4,5
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Service de Biostatistique et d’Informatique Médicale (DIM), CHRU Dijon, Dijon, France
Service de santé Publique, CHU Clermont-Ferrand, EA PEPRADE4681 Université d’Auvergne, Clermont-Ferrand, France
Dispensaire Emile Roux, Centre d’Aide à I’Arrêt du Tabagisme (IRAAT), Centre de Lutte Anti-Tuberculeuse (CLAT), Clermont-Ferrand, France
INSERM, CIC 1432, Dijon, France; Dijon University Hospital, Clinical Investigation Center, Clinical epidemiology/clinical trials unit, Dijon, France
Inserm UMR 1181 « Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases » (B2PHI), Univ. Bourgogne Franche-Comté, Dijon, France
Submission date: 2016-04-13
Acceptance date: 2016-10-21
Publication date: 2016-11-03
Corresponding author
C. Quantin   

Service de Biostatistique et d’Informatique Médicale (DIM), CHRU Dijon, Dijon F-21000, France
Tobacco Induced Diseases 2016;14(November):34
Hard core smokers have been studied in many countries but only a few trials have compared the effectiveness of smoking cessation with other smokers. The objective of this study was to compare the frequencies of success in smoking cessation between hard-core smokers and other smokers.

Data were collected in Clermont-Ferrand from the Emile Roux dispensary ‘Pneumology and Tobaccology Centre’ between 1999 and 2009. Assistance with smoking cessation was proposed to 1367 patients but only 1296 patients were included: 219 HCS and 1077 other smokers. Smoking cessation was considered a success when patients were abstinent 6 months after the beginning of cessation. The profiles of the two types of smokers were compared using Chi square test and Student’s t test. Multivariate logistic regression was used to investigate the association between the smoking cessation result and the type of smokers.

HCS more frequently consumed other psychoactive substances (41.1 % vs 25.7 % for other smokers; p < 0.001). Current depression was more frequent in HCS (46.6 % vs 34.8 % for other smokers; p = 0.001). Smoking cessation was less frequent in HCS (45.2 % vs 56.5 % for other smokers ; p = 0.002). In multivariate analysis, after controlling for other factors, the frequency of smoking cessation was not significantly associated with the type of smokers (p = 0.47). After limiting to initial factors (present before the beginning of smoking cessation), the frequency of smoking cessation was still not significantly associated with the type of smokers (p = 0.78).

Smoking cessation is possible for hard core smokers, who should be treated as other types of smokers taking into account other factors:the problem is how to encourage them to try to stop smoking.

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