The health effects of menthol cigarettes as compared to non-menthol cigarettes
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Center for Tobacco Products, Food and Drug Administration, Rockville, USA
Allison C. Hoffman   

Center for Tobacco Products, Food and Drug Administration, Rockville, MD 20850, USA
Publish date: 2011-05-23
Tobacco Induced Diseases 2011;9(Suppl 1):S7
Since the 1920s, menthol has been added to cigarettes and used as a characterizing flavor. The health effects of cigarette smoking are well documented, however the health effects of menthol cigarettes as compared to non-menthol cigarettes is less well studied. This review discusses menthol’s effects on 1) biomarkers of tobacco smoke exposure, 2) toxicity and cellular effects, 3) lung function and respiration, 4) pulmonary and/or vascular function, 5) allergic reactions and inflammation, and 6) tobacco-related diseases. It is concluded that menthol is a biologically active compound that has effects by itself and in conjunction with nicotine, however much of the data on the other areas of interest are inconclusive and firm conclusions cannot be drawn.
Centers for Disease Control and Prevention: Smoking-attributable mortality, years of potential life lost, and productivity losses—United States, 2000–2004. Morbidity and Mortality Weekly Report. 2008, 57 (45): 1226-1228.
U.S. Department of Commerce Census Bureau: National Cancer Institute and Centers for Disease Control and Prevention Co-sponsored Tobacco Use Supplement to the Current Population Survey (2006-07). Available at:
Giovino GA, Sidney S, Gfroerer JC, et al: Epidemiology of menthol cigarette use. Nicotine Tob. Res. 2004, 6 (Suppl 1): S67-81. 10.1080/14622203710001649696.
Ahijevych KL, Tyndale RF, et al: Factors influencing cotinine half-life during smoking abstinence in African American and Caucasian women. Nicotine and Tobacco Research. 2002, 4 (4): 423-431. 10.1080/1462220021000018452.
Caraballo RS, Giovino GA, et al: Racial and ethnic differences in serum cotinine levels of cigarette smokers—Third National Health and Nutrition Examination Survey, 1988–1991. JAMA. 1998, 280 (2): 135-139. 10.1001/jama.280.2.135.
Gan WQ, Cohen SB, et al: Sex-related differences in serum cotinine concentrations in daily cigarette smokers. Nicotine and Tobacco Research. 2008, 10 (8): 1293-1300. 10.1080/14622200802239132.
Benowitz NL, Herrera B, Jacob P: Mentholated cigarette smoking inhibits nicotine metabolism. J Pharmacol Exp Ther. 2004, 310 (3): 1208-1215. 10.1124/jpet.104.066902.
MacDougall JM, Fandrick K, et al: Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues. Chemical Research in Toxicology. 2003, 16 (8): 988-993. 10.1021/tx0340551.
Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF: Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers. Clin Pharmacol Ther. 2009, 85 (6): 635-643. 10.1038/clpt.2009.19.
Clark PI, Gautam S, et al: Effect of menthol cigarettes on biochemical markers of smoke exposure among black and white smokers. Chest. 1996, 110 (5): 1194-1198. 10.1378/chest.110.5.1194.
Ahijevych K, Parsley LA: Smoke constituent exposure and stage of change in Black and White women cigarette smokers. Addictive Behaviors. 1999, 24 (1): 115-120. 10.1016/S0306-4603(98)00031-8.
Ahijevych K, Wewers ME: Factors associated with nicotine dependence among African American women cigarette smokers. Research in Nursing and Health. 1993, 16 (4): 283-292. 10.1002/nur.4770160407.
Henningfield JE, Benowitz NL, et al: Does menthol enhance the addictiveness of cigarettes? An agenda for research. Nicotine and Tobacco Research. 2003, 5 (1): 9-11. 10.1080/1462220031000070543.
Perez-Stable EJ, Herrera B, et al: Nicotine metabolism and intake in Black and White smokers. JAMA. 1998, 280 (2): 152-156. 10.1001/jama.280.2.152.
Wagenknecht LE, Cutter GR, et al: Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study. American Journal of Public Health. 1990, 80 (9): 1053-1056. 10.2105/AJPH.80.9.1053.
Benowitz NL: Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. Clinical Pharmacology and Therapeutics. 2008, 83 (4): 531-541. 10.1038/clpt.2008.3.
Muscat JE, Chen G, et al: Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL Glucuronidation. Cancer Epidemiol Biomarkers Prev. 2009, 18 (1): 35-41. 10.1158/1055-9965.EPI-08-0744.
Patterson F, et al: Individual Differences in Nicotine Intake Per Cigarette. Cancer Epidemiol Biomarkers Prev. 2003, 12: 468-471.
Mustonen TK, Spencer SM, et al: The influence of gender, race, and menthol content on tobacco exposure measures. Nicotine and Tobacco Research. 2005, 7 (4): 581-590. 10.1080/14622200500185199.
Wang J, Roethig HJ, et al: The effect of menthol containing cigarettes on adult smokers’ exposure to nicotine and carbon monoxide. Regul Toxicol Pharmacol. 2010, 57 (1): 24-30. 10.1016/j.yrtph.2009.12.003.
Ahijevych K, Garrett BE: Menthol pharmacology and its potential impact on cigarette smoking behavior. Nicotine and Tobacco Research. 2004, 6 (suppl 1): S17-S28. 10.1080/14622200310001649469.
Heck JD: Smokers of menthol and nonmenthol cigarettes exhibit similar levels of biomarkers of smoke exposure. Cancer Epidemiol Biomarkers Prev. 2009, 18 (2): 622-629. 10.1158/1055-9965.EPI-08-0550.
Signorello L, Cai Q, et al: Racial differences in serum cotinine levels of smokers. Dis Markers. 2009, 27 (5): 187-192.
Williams JM, Gandhi KK, Steinberg ML, Foulds J, Ziedonis DM, Benowitz NL: Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. Nicotine and Tobacco Research. 2007, 9 (8): 873-881. 10.1080/14622200701484995.
Jarvik ME, Tashkin DP, et al: Mentholated cigarettes decrease puff volume of smoke and increase carbon monoxide absorption. Physiology and Behavior. 1994, 56 (3): 563-70. 10.1016/0031-9384(94)90302-6.
Miller GE, Jarvik ME, et al: Cigarette mentholation increases smokers’ exhaled carbon monoxide levels. Experimental and Clinical Psychopharmacology. 1994, 2 (2): 154-160. 10.1037/1064-1297.2.2.154.
Caskey NH, Jarvik ME, et al: Rapid smoking of menthol and nonmenthol cigarettes by Black and White smokers. Pharmacol Biochem Behav. 1993, 46 (2): 259-263. 10.1016/0091-3057(93)90350-3.
McCarthy WJ, Caskey NH, et al: Menthol vs. nonmenthol cigarettes: effects on smoking behavior. American Journal of Public Health. 1995, 85 (1): 67-72. 10.2105/AJPH.85.1.67.
Nil R, Battig K: Separate effects of cigarette smoke yield and smoke taste on smoking behavior. Psychopharmacology (Berl). 1989, 99 (1): 54-59. 10.1007/BF00634452.
Ahijevych K, Gillespie J, et al: Menthol and nonmenthol cigarettes and smoke exposure in Black and White women. Pharmacol Biochem Behav. 1996, 53 (2): 355-360. 10.1016/0091-3057(95)02034-9.
Rosenblatt MR, Olmstead RE, Iwamoto-Schaap PN, Jarvik ME: Olfactory thresholds for nicotine and menthol in smokers (abstinent and nonabstinent) and nonsmokers. Physiology and Behavior. 1998, 65 (3): 575-9. 10.1016/S0031-9384(98)00193-0.
Schmeltz I, Schlotzhauer WS: Benzo(a)pyrene, phenols and other products from pyrolysis of the cigarette additive, (d,1)-menthol. Nature. 1968, 219 (5152): 370-371. 10.1038/219370b0.
Rabinoff M, Caskey N, et al: Pharmacological and chemical effects of cigarette additives. American Journal of Public Health. 2007, 97 (11): 1981-1991. 10.2105/AJPH.2005.078014.
Richie JP, Carmella SG, et al: Differences in the urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in Black and White smokers. Cancer Epidemiol Biomarkers Prev. 1997, 6 (10): 783-790.
Gaworski CL, Dozier MM, et al: 13-week inhalation toxicity study of menthol cigarette smoke. Food and Chemical Toxicology. 1997, 35 (7): 683-692. 10.1016/S0278-6915(97)00033-1.
Azzi C, Zhang J, et al: Permeation and reservoir formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene (B[a]P) across porcine esophageal tissue in the presence of ethanol and menthol. Carcinogenesis. 2006, 27 (1): 137-145. 10.1093/carcin/bgi173.
Alakayak J, Knall C: Mentholated and non-mentholated cigarettes alter transepithelial electrical resistance of calu-3 human bronchial epithelial cells. Ethnicity and Disease. 2008, 18 (2 suppl 1): S145-S146.
Squier CA, Mantz MJ, Wertz PW: Effect of menthol on the penetration of tobacco carcinogens and nicotine across porcine oral mucosa ex vivo. Nicotine and Tobacco Research. 2010, e-pub ahead of print.
Bernson VS, Pettersson B: The toxicity of menthol in short-term bioassays. Chemico-Biological Interactions. 1983, 46 (2): 233-246. 10.1016/0009-2797(83)90031-5.
Bernhardt G, Biersack B, et al: Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chemistry and Biodiversity. 2008, 5 (8): 1645-1659. 10.1002/cbdv.200890152.
Kim SH, Nam JH, et al: Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. Biochimica et Biophysica Acta. 2009, 1792 (1): 33-38.
Li Q, Wang X, et al: Menthol induces cell death via the TRPM8 channel in the human bladder cancer cell line T24. Oncology. 2009, 77: 335-341. 10.1159/000264627.
Lin JP, Lu HF, et al: (-)-Menthol inhibits DNA topoisomerases I, II alpha and beta and promotes NF-kappaB expression in human gastric cancer SNU-5 cells. Anticancer Research. 2005, 25 (3B): 2069-2074.
Lu HF, Hsueh SC, et al: The role of Ca2+ in (-)-menthol-induced human promyelocytic leukemia HL-60 cell death. In Vivo. 2006, 20 (1): 69-75.
Lu HF, Liu JY, et al: (-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo. In Vivo. 2007, 21 (2): 285-289.
Ruch RJ, Sigler K: Growth inhibition of rat liver epithelial tumor cells by monoterpenes does not involve Ras plasma membrane association. Carcinogenesis. 1994, 15 (4): 787-789. 10.1093/carcin/15.4.787.
Sidell N, Verity MA, et al: Menthol blocks dihydropyridine-insensitive Ca2+ channels and induces neurite outgrowth in human neuroblastoma cells. Journal of Cellular Physiology. 1990, 142 (2): 410-419. 10.1002/jcp.1041420226.
Sidell N, Taga T, et al: Retinoic acid-induced growth inhibition of a human myeloma cell line via down-regulation of IL-6 receptors. J Immunol. 1991, 146 (11): 3809-3814.
Tatman D, Mo H: Volatile isoprenoid constituents of fruits, vegetables and herbs cumulatively suppress the proliferation of murine B16 melanoma and human HL-60 leukemia cells. Cancer Letters. 2002, 175 (2): 129-139. 10.1016/S0304-3835(01)00723-6.
Yamamura H, Ugawa S, et al: TRPM8 activation suppresses cellular viability in human melanoma. American Journal of Physiology: Cell Physiology. 2008, 295 (2): C296-C301. 10.1152/ajpcell.00499.2007.
Zhang L, Barritt GJ: Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. Cancer Research. 2004, 64 (22): 8365-8373. 10.1158/0008-5472.CAN-04-2146.
Gordon WP, Forte AJ, et al: Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse. Toxicology and Applied Pharmacology. 1982, 65 (3): 413-424. 10.1016/0041-008X(82)90387-8.
Doolittle DJ, Lee CK, et al: Comparative studies on the genotoxic activity of mainstream smoke condensate from cigarettes which burn or only heat tobacco. Environmental and Molecular Mutagenesis. 1990, 15 (2): 93-105. 10.1002/em.2850150206.
Doolittle DJ, Lee CK, et al: Genetic toxicology studies comparing the activity of sidestream smoke from cigarettes which burn or only heat tobacco. Mutation Research. 1990, 240 (2): 59-72. 10.1016/0165-1218(90)90008-P.
Lee CK, Doolittle DJ, et al: Comparative genotoxicity testing of mainstream whole smoke from cigarettes which burn or heat tobacco. Mutation Research. 1990, 242 (1): 37-45. 10.1016/0165-1218(90)90097-L.
Roemer E, Tewes FJ, Meisgan TJ, et al: Evaluation of the potential effects of ingredients added to cigarettes. Part 3: In vitro genotoxcity and cytotoxicity. Food and Chemical Toxicology. 2002, 40: 105-111. 10.1016/S0278-6915(01)00086-2.
Baker RR, Massey ED, Smith G: An overview of the effects of tobacco ingredients on smoke chemistry and toxicity. Food Chem Toxicol. 2004, 42 Suppl: S53-S83. 10.1016/j.fct.2004.01.001.
Saint Charles FK, Krautter GR, Mariner DC: Post-puff respiration measures on smokers of different tar yield cigarettes. Inhalation Toxicology. 2009, 21 (8): 712-718. 10.1080/08958370802353443.
Scanlon PD, Connett JE, et al: Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease: the lung health study. American Journal of Respiratory and Critical Care Medicine. 2000, 161: 381-390.
Wayne GF, Connolly GN, et al: Assessing internal tobacco industry knowledge of the neurobiology of tobacco dependence. Nicotine and Tobacco Research. 2004, 6 (6): 927-940. 10.1080/14622200412331324839.
Eccles R, Lancashire B, et al: The effect of aromatics on inspiratory and expiratory nasal resistance to airflow. Clinical Otolaryngology and Allied Sciences. 1987, 12 (1): 11-14. 10.1111/j.1365-2273.1987.tb00157.x.
Eccles R, Jawad MS, et al: The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. Journal of Pharmacy and Pharmacology. 1990, 42 (9): 652-654. 10.1111/j.2042-7158.1990.tb06625.x.
Nishino T, Tagaito Y, et al: Nasal inhalation of l-menthol reduces respiratory discomfort associated with loaded breathing. American Journal of Respiratory and Critical Care Medicine. 1997, 156 (1): 309-313.
Pletcher MJ, Hulley BJ, et al: Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Archives of Internal Medicine. 2006, 166 (17): 1915-1922. 10.1001/archinte.166.17.1915.
Ciftci O, Caliskan M, et al: Mentholated cigarette smoking induced alterations in left and right ventricular functions in chronic smokers. Anadolu Kardiyoloji Dergisi. 2008, 8 (2): 116-122.
Ciftci O, Gullu H, et al: Mentholated cigarette smoking and brachial artery, carotid artery, and aortic vascular function. Archives of the Turkish Society of Cardiology. 2009, 37 (4): 234-240.
Ciftci O, Topcu S, et al: Smoking mentholated cigarettes impairs coronary microvascular function as severely as does smoking regular cigarettes. Acta Cardiologica. 2008, 63 (2): 135-140. 10.2143/AC.63.2.2029518.
Pritchard WS, Houlihan ME, et al: Little evidence that “denicotinized” menthol cigarettes have pharmacological effects: an EEG/heart-rate/sujective-response study. Psychopharmacology (Berl). 1999, 143 (3): 273-279. 10.1007/s002130050947.
National Cancer Institute: Bioassay of DL-Menthol for Possible Carcinogenicity. National Cancer Institute Carcinogenesis Technical Report Series No 98 (NCI-CG-TR-98). 1979.
Ashby J, Tennant RW: Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutat Res. 1991, 257 (3): 229-306. 10.1016/0165-1110(91)90003-E.
Ishidate M, Sofuni T, Yoshikawa K, Hayashi M, Nohmi T, Sawada M, et al: Primary mutagenicity screening of food additives currently used in Japan. Food and Chemical Toxicology. 1984, 22 (8): 623-636. 10.1016/0278-6915(84)90271-0.
Ivett JL, Brown BM, Rodgers C, Anderson BE, Resnick MA, Zeiger E: Chromosomal aberrations and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals. Environmental and Molecular Mutagenesis. 1989, 14: 165-187. 10.1002/em.2850140306.
Murthy PBK, Ahmed MM, Regu K: Lack of genotoxicity of menthol in chromosome aberration and sister chromatid exchange assays using human lynphocytes in vitro. Toxicology in Vitro. 1991, 5 (4): 337-340. 10.1016/0887-2333(91)90010-B.
Gaworski CL, Heck JD, et al: Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice. Toxicology. 1999, 139 (1-2): 1-17. 10.1016/S0300-483X(99)00094-3.
Wattenberg LW: Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol). Carcinogenesis. 1991, 12 (1): 151-152. 10.1093/carcin/12.1.151.
Russin WA, Hoesly JD, et al: Inhibition of rat mammary carcinogenesis by monoterpenoids. Carcinogenesis. 1989, 10 (11): 2161-2164. 10.1093/carcin/10.11.2161.
Brooks DR, Palmer JR, et al: Menthol cigarettes and risk of lung cancer. American Journal of Epidemiology. 2003, 158 (7): 609-616. 10.1093/aje/kwg182.
Friedman GD, Sadler M, et al: Mentholated cigarettes and non-lung smoking related cancers in California, USA. Journal of Epidemiology and Community Health. 1998, 52 (3): 202-10.1136/jech.52.3.202.
Hebert JR, Kabat GC: Menthol cigarettes and esophageal cancer. American Journal of Public Health. 1988, 78 (8): 986-987. 10.2105/AJPH.78.8.986.
Kabat GC, Hebert JR: Use of mentholated cigarettes and lung cancer risk. Cancer Research. 1991, 51 (24): 6510-6513.
Murray RP, Connett JE, Skeans MA, Tashkin DP: Menthol cigarettes and health risks in Lung Health Study data. Nicotine and Tobacco Research. 2007, 9 (1): 101-107. 10.1080/14622200601078418.
Sidney S, Tekawa IS, et al: Mentholated cigarette use and lung cancer. Archives of Internal Medicine. 1995, 155 (7): 727-732. 10.1001/archinte.155.7.727.
Kabat GC, Hebert JR: Use of mentholated cigarettes and oropharyngeal cancer. Epidemiology. 1994, 5 (2): 183-188. 10.1097/00001648-199403000-00008.
Hebert JR, Kabat GC: Menthol cigarette smoking and oesophageal cancer. International Journal of Epidemiology. 1989, 18 (1): 37-44. 10.1093/ije/18.1.37.
Carpenter CL, Jarvik ME: Mentholated cigarette smoking and lung-cancer risk. Annals of Epidemiology. 1999, 114-120. 10.1016/S1047-2797(98)00042-8. 2.
Stellman SD, Chen Y, et al: Lung cancer risk in White and Black Americans. Annals of Epidemiology. 2003, 13 (4): 294-302. 10.1016/S1047-2797(02)00420-9.
Etzel CJ, Kachroo S, et al: Development and validation of a lung cancer risk prediction model for African-Americans. Cancer Prevention Research. 2008, 1 (4): 255-265. 10.1158/1940-6207.CAPR-08-0082.
Garten S, Falkner RV: Continual smoking of mentholated cigarettes may mask the early warning symptoms of respiratory disease. Preventive Medicine. 2003, 37 (4): 291-296. 10.1016/S0091-7435(03)00116-6.
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