Gender differences in tobacco use disorder phenotypes among smokers in the largest metropolitan area of South America
| 1 | University of São Paulo, Psychiatry, Brazil |
| 2 | Columbia University Mailman School of Public Health, Epidemiology, United States of America |
Publication date: 2018-03-01
Tob. Induc. Dis. 2018;16(Suppl 1):A363
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Download abstract book (PDF)ABSTRACT
Background:
Given the gender differences that permeate Tobacco Use Disorders (TUD), we aimed to identify phenotypes of TUD in female and male in a representative sample of smokers in a developing country.
Methods:
Data came from lifetime weekly smokers ages 18 and older taking part in the São Paulo Megacity Mental Health Survey collected between 2005-2007 (n = 1,386). Latent class analysis (LCA) was performed on nine TUD criteria stratified by gender. Logistic regression models explored the association between latent classes and socio-demographic and psychiatric variables. All analysis were performed using Mplus taking into account sampling weights and complex survey design features.
Results:
The best fitting LCA model had three classes within a severity continuum in both genders: a “non-symptomatic class”(Women[W]:30.2% , Men [M]: 44.4%), a “moderate symptomatic class”(W:45.5% , M:30.7%), and a “high-moderate symptomatic class”(W: 24.3%, M: 24.7%). Respondents in the “moderate symptomatic class” were more likely to have higher household income among female, and high-average education among male than those in the “non-symptomatic class”. Both women and men in the “high-moderate symptomatic class” were more likely to have past-year anxiety, but only men were more likely to have past-year insomnia than those in the “non-symptomatic class”.
Conclusions:
Both men and women smokers are divided into three TUD phenotypes, with approximately a quarter being highly dependent, which is associated with psychiatric comorbidity. However, women are more vulnerable to experiencing lifetime TUD symptomatology: 70%, in contrast to 56% of men. The intermediate symptomatic phenotype in women was associated with high income, which may show an important differential in the smoking behaviors paradigm in this developing country.
Given the gender differences that permeate Tobacco Use Disorders (TUD), we aimed to identify phenotypes of TUD in female and male in a representative sample of smokers in a developing country.
Methods:
Data came from lifetime weekly smokers ages 18 and older taking part in the São Paulo Megacity Mental Health Survey collected between 2005-2007 (n = 1,386). Latent class analysis (LCA) was performed on nine TUD criteria stratified by gender. Logistic regression models explored the association between latent classes and socio-demographic and psychiatric variables. All analysis were performed using Mplus taking into account sampling weights and complex survey design features.
Results:
The best fitting LCA model had three classes within a severity continuum in both genders: a “non-symptomatic class”(Women[W]:30.2% , Men [M]: 44.4%), a “moderate symptomatic class”(W:45.5% , M:30.7%), and a “high-moderate symptomatic class”(W: 24.3%, M: 24.7%). Respondents in the “moderate symptomatic class” were more likely to have higher household income among female, and high-average education among male than those in the “non-symptomatic class”. Both women and men in the “high-moderate symptomatic class” were more likely to have past-year anxiety, but only men were more likely to have past-year insomnia than those in the “non-symptomatic class”.
Conclusions:
Both men and women smokers are divided into three TUD phenotypes, with approximately a quarter being highly dependent, which is associated with psychiatric comorbidity. However, women are more vulnerable to experiencing lifetime TUD symptomatology: 70%, in contrast to 56% of men. The intermediate symptomatic phenotype in women was associated with high income, which may show an important differential in the smoking behaviors paradigm in this developing country.
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